The CHIPS and Science Act is one of the most significant pieces of science legislation in years. With $180 billion for research and development over the next five years, it aims to bolster the semiconductor industry as well as federal science agencies like the National Science Foundation and Department of Energy. But now comes what many observers view as the hardest part: not only must the money be appropriated, but the act must be implemented in a way that meets its many objectives. In the journal Issues in Science and Technology, several experts explore the ways the CHIPS and Science Act can deliver on its promises to spur innovation, strengthen regional economies and workforce, and promote US competitiveness. In addition, there will be a webinar on November 1st at 3 p.m. where these experts discuss how implementation of this important legislation can best meet—and balance—its many goals.